Chlorhexidine Mouthrinses and Plaque Control

Hôpital Militaire De Rabat

Status

Completed

Conditions

Dental Plaque

Treatments

Drug: Synthodont

Drug: Soludent

Study type

Interventional

Funder types

Other

Identifiers

NCT01138943

1251/10

1171

Details and patient eligibility

About

The aim of the present study was to compare antiplaque effectiveness of two commercial mouthrinses: 0.12 % Chlorhexidine alcohol base (CLX-A) versus a diluted 0.1% Chlorhexidine non-alcohol base with 0.1% of Formaldehyde (CLX-F).

Full description

Chlorhexidine (CLX) mouthrinse has been the gold standard as antiplaque solution.However, if its efficiency seems to be preserved even if the chlorhexidine concentration is bellow 0.10%, the formulation of the final product may affect the effectiveness. Thus, it can be concluded from this study that 0.12% CLX alcohol base mouthrinse is significantly more effective in inhibiting plaque than the diluted 0.1% CLX non-alcohol base containing formaldehyde mouthrinse.

Enrollment

30 patients

Sex

All

Ages

20 to 25 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

give written informed consent before entering the study
accept to stop tooth cleaning for a week

Exclusion criteria

less than 20 teeth;
presence of periodontal disease
presence of factors of plaque retention (clinically unacceptable restorations, important carious, dental overlapping, removable prosthesis, faulty fixed prosthesis, orthodontic appliances),
associated systemic diseases (diabetes, heart disorders, blood diseases, HIV infection),
use of antibiotics or other anti-inflammatory drugs during the latest months,
known allergy against components of mouth rinses,
pregnancy,
smoking