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Chocolate's Effect on the Cerebral Vasculature

NHS Trust logo

NHS Trust

Status

Completed

Conditions

Cerebral Vasculature

Treatments

Other: cocoa

Study type

Observational

Funder types

Other

Identifiers

NCT01507259
GN11MT497

Details and patient eligibility

About

The popularity of chocolate can largely be attributed to its mood elevating properties, research shows that it contains antioxidants that also provide physical health benefits. Dark chocolate, in particular, contains high levels of an antioxidant called epicatechin, which is known to cause changes in blood vessels by relaxing them and increasing blood flow.

Little is know about the immediate effects of chocolate consumption, or the differences between milk and dark chocolate with regards to these effects. The project will investigate the effect of a single bar of dark or milk chocolate upon blood flow to the brain, using simple ultrasound tests.

Enrollment

24 patients

Sex

All

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • No regular medication including vitamins/antioxidants
  • Able to provide informed consent

Exclusion criteria

  • Inability to perform breath-hold test
  • Any known cardiovascular disease, diabetes, throid disease, high blood pressure, hyperlipidaemia or pregnancy

Trial design

24 participants in 1 patient group

100 g containing 70% or 34% cocoa
Description:
Healthy controls
Treatment:
Other: cocoa

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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