Choosing the Right Pacing Mode in Heart Failure - The CHOICE Trial

U

University of Dundee

Status

Completed

Conditions

Heart Failure

Treatments

Device: Bi Ventricular Pacing
Device: Right Ventricular Pacing

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT00875732
ELD001

Details and patient eligibility

About

The aim of the study is to see if biventricular pacemakers offer any advantage over conventional pacemakers in patients with heart failure who require pacemakers. The endpoints will be the 6 minute walking distance along with markers of cardiovascular function. The investigators' hypothesis is that biventricular pacing is preferable to conventional pacing in these heart failure patients.

Enrollment

22 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Left ventricular systolic dysfunction.
  2. Atrio-ventricular node disease.
  3. Anticipated to be more than 40% paced, (including patients in permanent atrial fibrillation).
  4. Ability to walk independently (walking aid permitted).

Exclusion criteria

  1. Patients meeting criteria for CRT by current guidelines will be excluded.
  2. Life expectancy less than12 months.
  3. Inability to walk independently.
  4. Patients not likely to be compliant with follow-up.
  5. Bradyarrhythmia due with sino-atrial disease only.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Quadruple Blind

22 participants in 2 patient groups

1
Experimental group
Description:
Biventricular Pacing
Treatment:
Device: Bi Ventricular Pacing
2
Active Comparator group
Description:
Right Ventricular Pacing
Treatment:
Device: Right Ventricular Pacing

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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