Chorioretinal Vascularization and Electrophysiological Changes After Carotid Revascularization (CAS-AOCT)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: Carotid Stenosis

Treatments: Diagnostic Test: Optical coherence tomography angiography and pattern electroretinogram

Study type: Interventional

Funder types: Other

Identifiers

NCT05835869

5532

Details and patient eligibility

About

The aim of the study is to evaluate changes in retinal function by means of electro-functional examinations of the retina and to associate them with any changes in chorioretinal vascular density occurring in the ipsilateral eye after carotid revascularization surgery.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age >18 years old
• Carotid stenosis diagnosis with indication to perform carotid endarterectomy
• informed consent form signing

Exclusion criteria

• age <18 years old
• recurrent intraocular inflammation
• retinal disease
• optic neuropathy, optic nerve drusen, opacity of the dioptric means in the pre- or post-operative period that prevents the acquisition of high-resolution images
• unstable fixation
• spheric refractive error > +/- 6 D spheric and/or +/- 3 D cylinder
• history of prior ocular surgery
• refusal of signing informed consent form

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Study population

Experimental group

Treatment:

Diagnostic Test: Optical coherence tomography angiography and pattern electroretinogram