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International recommendations support dynamic or isometric strength training as an adjunct to aerobic exercise. Given the lack of consensus, this study aims to evaluate the chronic effects of isometric exercise, performed through handgrip or isometric knee extension, as a hypotensive strategy in adults with hypertension.
Full description
This study is designed as a randomized, controlled, evaluator-blinded clinical trial, conducted entirely at the Laboratory of Clinical Investigation (LCI) of the Cardiology Institute of Rio Grande do Sul / University Foundation of Cardiology (ICFUC). The project follows all recommendations of the CONSORT Statement.
Male and female participants aged 40 to 70 years, with blood pressure ≥ 120/80 mmHg, will be enrolled. After signing informed consent, participants will complete a questionnaire to assess their habitual physical activity level and will undergo isometric handgrip or isometric knee extension training for 4 weeks. Blood pressure will be assessed at baseline and after the intervention using ambulatory blood pressure monitoring (ABPM).
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Inclusion criteria
Patients with controlled hypertension under medication. Sedentary or physically inactive individuals.
Exclusion criteria
Pregnant women. Unstable angina. Heart failure classified as NYHA class II, III, or IV. Recent cardiovascular event within the last 3 months. Chronic renal insufficiency. Diabetes mellitus. History of malignant disease with a life expectancy of less than 2 years. Orthopedic, physical, or mental limitations that prevent the performance of physical exercise.
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Interventional model
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66 participants in 3 patient groups
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Data sourced from clinicaltrials.gov
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