Chronic Resveratrol Supplementation in Healthy Humans

Northumbria University

Status and phase: Completed; Phase 1

Conditions: Healthy

Treatments: Dietary Supplement: Resveratrol; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01640197

22P4

Details and patient eligibility

About

The effects of chronic resveratrol supplementation have yet to be investigated in healthy humans. It is hypothesised that the effects will be different to those seen in acute supplementation. This study will look specifically at cognitive performance, cerebral blood flow, subjective sleep, mood and health, blood pressure and plasma levels of resveratrol. It is hypothesized that these measures will be affected differently by acute and chronic supplementation.

Enrollment: 60 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Between 18-35
• At least enrolled on undergraduate degree programme
• Native English speaker

Exclusion criteria

• Smoking
• Taking other medication/ supplements
• Pregnant/ breast feeding
• High caffeine consumers
• Migraine sufferers

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Methyl Cellulose administered in identical capsules as the active.

Treatment:

Other: Placebo

500mg resveratrol

Active Comparator group

Description:

Transmax from biotivia. 500mg resveratrol (98% purity) with 10mg piperine per capsule. 1 capsule taken daily.

Treatment:

Dietary Supplement: Resveratrol