ChronoMet: Metabolic and Inflammatory Effects of Eating Timing and Quantity

University of Minnesota (UMN)

Status: Enrolling

Conditions: Healthy Volunteers

Treatments: Dietary Supplement: Meals

Study type: Interventional

Funder types: Other

Identifiers

NCT06161337

MED-2023-32162

Details and patient eligibility

About

This is an observational study to address the important knowledge gap of the metabolic and inflammatory impact of acute overeating and whether timing of acute overeating may modify these effects. The hypothesis is that acute overconsumption of calories will promote inflammation and metabolic dysfunction, with the most detrimental effects observed with evening caloric overconsumption. The expectation is that this study to provide critical insights into the biological consequences of overeating, which will direct novel approaches combating overeating and its detrimental health effects.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ages of 18-65 years old
• not pregnant
• no comorbid conditions
• normal BMI (18.5 - 24.9 kg/m2)
• Weight ≥120 lbs self-reported weight

Exclusion criteria

• N/A

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

Experimental group

Experimental group

Description:

60 young (age 18-65), healthy, normal body mass index subjects for this study.

Treatment:

Dietary Supplement: Meals