Cigarette and E-cigarette Flavors Manipulations in the Experimental Tobacco Marketplace

Virginia Polytechnic Institute and State University

Status: Completed

Conditions: Tobacco Use Disorder

Treatments: Behavioral: Cigarette flavor unrestricted and e-cigarette flavor unrestricted; Behavioral: Cigarette flavor restricted and e-cigarette flavor restricted; Behavioral: Cigarette flavor unrestricted and e-cigarette flavor restricted; Behavioral: Cigarette flavor restricted and e-cigarette flavor unrestricted

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05110872

P01CA217806 (U.S. NIH Grant/Contract)

VT IRB# 20-827

Details and patient eligibility

About

This is a one-session study that participants complete remotely including consent, Experimental Tobacco Marketplace purchases, and assessments to examine the effects of cigarette and e-cigarette flavors on cigarette demand and substitution in the Experimental Tobacco Marketplace.

Full description

This study uses a mixed design (within-subject repeated measures and between-group). Participants will be assigned to two different groups according to their preferred cigarette flavor (tobacco/menthol). Every participant will complete behavioral tasks and make hypothetical purchases of tobacco products in an online store under four different scenarios: a) e-cigarette flavor restricted and cigarette flavor restricted, b) e-cigarette flavor unrestricted and cigarette flavor restricted, c) e-cigarette flavor restricted and cigarette flavor unrestricted, d) e-cigarette flavor unrestricted and cigarette flavor unrestricted.

Enrollment: 302 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• currently smoke at least 10 cigarettes per day
• have smoked at least 100 cigarettes (lifetime), and
• are 21 years of age or older.

Exclusion criteria

• inaccurate identification of usual brand of cigarette's as menthol or non-menthol

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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302 participants in 2 patient groups

Menthol cigarette smokers

Experimental group

Description:

Adults (21 y.o. and older) who smoke ate least 10 menthol cigarettes per day will be recruited.

Treatment:

Behavioral: Cigarette flavor restricted and e-cigarette flavor unrestricted

Behavioral: Cigarette flavor unrestricted and e-cigarette flavor restricted

Behavioral: Cigarette flavor unrestricted and e-cigarette flavor unrestricted

Behavioral: Cigarette flavor restricted and e-cigarette flavor restricted

Non-menthol cigarette smokers

Experimental group

Description:

Adults (21 y.o. and older) who smoke ate least 10 non-menthol cigarettes per day will be recruited.

Treatment:

Behavioral: Cigarette flavor restricted and e-cigarette flavor unrestricted

Behavioral: Cigarette flavor unrestricted and e-cigarette flavor restricted

Behavioral: Cigarette flavor unrestricted and e-cigarette flavor unrestricted

Behavioral: Cigarette flavor restricted and e-cigarette flavor restricted