CIMT Versus HABIT in Late Sub-Acute Post-Stroke Rehabilitation (CIMT-HABIT)

Riphah International University

Status: Active, not recruiting

Conditions: Stroke

Treatments: Behavioral: Hand-Arm Bimanual Intensive Training; Behavioral: Constraint Induced Movement Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT07626554

HAFSA LATIF

Details and patient eligibility

About

This study will compare the effects of Constraint Induced Movement Therapy and Hand-Arm Bimanual Intensive Training on upper extremity function in late sub-acute post-stroke patients. It will be a randomized controlled trial. Eligible participants will be randomly allocated into two groups. One group will receive Constraint Induced Movement Therapy, while the other group will receive Hand-Arm Bimanual Intensive Training. Both groups will also receive standard physiotherapy for mobility and postural control. The intervention will continue for 3 weeks. Outcomes will be assessed at baseline and after the intervention using upper limb function and motor control assessment tools.

Full description

Stroke commonly affects upper extremity function and may reduce a patient's ability to perform daily activities independently. In the late sub-acute phase after stroke, structured rehabilitation may help improve arm and hand function, motor control, and real-world use of the affected upper limb. Constraint Induced Movement Therapy encourages use of the affected upper limb by restricting the unaffected arm and providing intensive task-oriented training. Hand-Arm Bimanual Intensive Training focuses on coordinated use of both hands through functional bimanual tasks. This study will compare these two rehabilitation approaches in late sub-acute post-stroke patients. Findings may help guide evidence-based selection of upper limb rehabilitation strategies for improving functional recovery after stroke.

Enrollment: 34 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Adults aged 40 years and above.

• Diagnosed with unilateral ischemic or hemorrhagic stroke.
• Stroke duration between 3 to 6 months.
• Mini-Mental State Examination score of 24 or above.
• Able and willing to provide informed consent.

Exclusion criteria

Severe pain in the more affected upper limb on verbal rating scale.

• Spasticity greater than 3 on the Modified Ashworth Scale in the affected upper limb.
• Unstable cardiovascular conditions.
• Any traumatic musculoskeletal injury of the upper limb.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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34 participants in 2 patient groups

Constraint Induced Movement Therapy Group

Experimental group

Description:

Participants in this arm will receive Constraint Induced Movement Therapy for 3 weeks. The unaffected arm will be constrained with a mitt for 90% of waking hours, and the affected arm will receive intensive task-oriented training for 2 hours per day, 5 days per week. Training tasks will include reaching, grasping, manipulating, dressing, and eating activities. Participants will also receive standard physiotherapy for mobility and postural control.

Treatment:

Behavioral: Constraint Induced Movement Therapy

Hand-Arm Bimanual Intensive Training Group

Active Comparator group

Description:

Participants in this arm will receive Hand-Arm Bimanual Intensive Training for 3 weeks. Training will be provided for 2 hours per day, 5 days per week, using symmetrical and asymmetrical bimanual activities such as folding clothes and pouring water. Participants will also receive standard physiotherapy for mobility and postural control.

Treatment:

Behavioral: Hand-Arm Bimanual Intensive Training