CIRCAdian Rhythm of the IMMune Age IndeX (IMMAX) (CIRCA-IMMAX)

Leibniz Research Centre for Working Environment and Human Factors

Status: Completed

Conditions: Immune Cells (Mucosal and Systemic); Healthy Subjects

Study type: Observational

Funder types: Other

Identifiers

NCT07169721

Ethics committee approval: 243

Details and patient eligibility

About

The goal of this observational study is to evaluate the influence of circadian rhythms on the determination of an individual's immune age. The biomarker IMMAX was calculated for 50 participants aged 20-69 at 8 a.m., 1 p.m. and 6 p.m. on the same day.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• aged > 18 years
• knowledge of German or English sufficient to provide verbal explanations and obtain written consent

Exclusion criteria

• exercise on the assessment day
• acute infection
• vaccination within the last 4 weeks
• autoimmune disease
• cancer
• drugs that may influence immune cell counts
• participation in other interventional studies during study period