ClinicalTrials.Veeva

Menu

Circuit and Resistance Training in COPD

R

Riphah International University

Status

Completed

Conditions

Chronic Obstructive Pulmonary Disease

Treatments

Other: Progressive Resistance
Other: Circuit Training

Study type

Interventional

Funder types

Other

Identifiers

NCT06601764
Zubair Khalid

Details and patient eligibility

About

Chronic Obstructive Pulmonary Disease (COPD) is characterized by a combination of pulmonary and extra-pulmonary manifestations that directly contribute to the increase in exercise intolerance and dyspnea, especially in more advanced stages of the disease, leading to physical inactivity and consequent worsening of these signs and symptoms. COPD is a preventable and treatable lung disease. Solid evidence shows that physical training, the most important component of a Pulmonary Rehabilitation program (PR), reduces dyspnea and fatigue, increases exercise performance, and improves peripheral muscle strength, functional capacity, control of emotional function and quality of life of these patients' lives. Multicomponent physical training (MPT) proposes the performance of 3 or more components or physical training modalities within the same session and has demonstrated its benefits in several studies involving the elderly population. The main objective of the study will be to determine the effects of circuit training and resistive exercises on pulmonary function and physical parameters in population with COPD.

The study will be a randomized clinical trial and conducted for a duration of 09 months after the approval of synopsis. Data will be collected with Non-Probability Convenience Sampling Technique. A sample of 48 COPD patients will be recruited from DHQ Muzaffargarh. This will be a double blinded study with patients and assessor blinded to the intervention. COPD patients will be divided into two groups with group 1 treated with circuit training and group 2 treated with resistance exercise for duration of 10 weeks. Baseline values for Respiratory parameters and physical parameters will be collected and after 5 weeks and 10 weeks of treatment. Data will be analyzed using SPSS v 26. For within the group analysis Repeated Measure ANOVA will be used. For across the group analysis, independent sample T test will be used to compare the mean differences.

Full description

Chronic obstructive pulmonary disease (COPD) is a progressive disease with deteriorating cardiopulmonary function that decreases the health-related quality of life (HRQL) and exercise capacity. Patients with COPD often have cardiovascular and muscular problems that hinder oxygen uptake by peripheral tissues, resulting in poor oxygen consumption efficiency. Only 20% of the estimated COPD cases are currently being identified and diagnosed in primary care in Pakistan.

Circuit training should be considered the most effective strategy to improve exercise capacity in patients with COPD. Supervision of the programs improves exercise capacity. Concerning strength outcome, the Circuit Training increased the strength of the upper and lower extremities. Only the magnitude of strength performance appears to be influenced by the training (number of sessions and frequency) and the training status. Moreover, low and moderate intensities and short rest time between exercises increase the magnitude of change in fat mass loss. Therefore, CT has been shown to be an effective method for improving body composition, cardio-respiratory fitness, and strength of the lower and upper limbs. Moreover, CT has been shown to elicit higher oxygen consumption during the session in comparison to a traditional strength-training session. Modalities of resistance training using elastic components presented similar effects on muscle strength, health status, exercise capacity, body composition and daily level of physical activity in individuals with COPD. The effects of elastic resistance were similar to conventional resistance training. CT significantly improves aerobic performance (i.e., increase maximum aerobic speed and aerobic performance) and VO2max (average 6.3%), showing that this type of training increases cardio-respiratory fitness independent of the training protocol. CT had an overall significant and large effect on upper (bench press) and lower strength (leg extension) performance (1-RM).only the magnitude of strength performance appears to be influenced by the training (i.e., number of sessions and frequency) and population characteristics (i.e., training status).

Enrollment

48 patients

Sex

All

Ages

40 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age range from 40 to 70 years
  • Clinical -functional diagnosis of COPD criteria GOLD II and III
  • Clinically stable (outside the period of exacerbation of the disease for at least 3 months),
  • Independently able to perform instrumental activities of daily living, as assessed by the functional activities questionnaire
  • No medical contraindications for physical exercise.

Exclusion criteria

  • Pulmonary diseases such as asthma, pulmonary fibrosis, pneumonia and other non-pulmonary
  • Sever or difficult to control ( heart disease or sequelae of acute or chronic orthopedic and/or neurological diseases),
  • Those who use walking assist devices that could influence the exercise
  • Enrolled in a physical training program within the last 3 months at baseline

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

48 participants in 2 patient groups

Group A: Circuit training
Experimental group
Description:
Circuits Training Exercise Group
Treatment:
Other: Circuit Training
Group B: Progressive Resistance Exercise Group
Active Comparator group
Description:
Progressive Resistance Exercise Group
Treatment:
Other: Progressive Resistance

Trial contacts and locations

1

Loading...

Central trial contact

Imran Amjad, PhD; Danish Hassan, PhD*

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems