Circuit Training and Retina

University of Miami

Status: Completed

Conditions: Cognitive Impairment, Progressive; Cerebral Small Vessel Diseases

Treatments: Behavioral: Lecture on Diet, Exercise and Cognition; Behavioral: High-Speed Circuit Resistance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT05714813

20210271

Details and patient eligibility

About

The purpose of this research study is to see if high-speed weight training performed in a circuit (using one machine after another) can improve participant heart and brain function, strength, and power in older persons.

Enrollment: 40 patients

Sex: All

Ages: 65 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. 65-90 years of age;
2. Montreal Cognitive Assessment (MoCA) > 23
3. no memory loss complaints

Exclusion criteria

1. Uncontrolled cardiovascular or neuromuscular diseases that prevent participation in a training program;
2. Cerebrovascular disease;
3. Malignancy within the previous 5 years;
4. Documented HIV infection or other immunodeficiency syndrome;
5. Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus, or other serious concomitant medical illness;
6. A history of ocular surgeries (except for cataract surgery more than 6 months ago) or other ocular diseases;
7. Bilateral moderate or severe cataracts;
8. Refractive errors of myopia, hyperopia and/or astigmatism more than 6.0 Diopters.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

High-Speed Circuit Resistance Training Group

Experimental group

Description:

Participants in this group will receive high-speed circuit resistance training 3 times a week for 24 consecutive weeks for a total of 72 training sessions.

Treatment:

Behavioral: High-Speed Circuit Resistance Training

Control Group

Other group

Description:

Participants in this arm will receive two lectures on fitness, diet, or cognition each month for 24 weeks for a total of 12 lectures.

Treatment:

Behavioral: Lecture on Diet, Exercise and Cognition