Circulating Endothelial Progenitor Cells and Aortic Aneurysm (ANOPEC3)

Hopital Jean Minjoz

Status: Unknown

Conditions: - Aortic Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT01918982

147/362

Details and patient eligibility

About

We aimed to see if aortic aneurysms could be followed-up by circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level.

Full description

Circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- have been shown to be inversely correlated to aortic aneurysm size. We aimed to see if aortic aneurysms could be followed-up by circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level. 40 patients followed for known aortic aneurysm >30mm and <50mm will be followed up every 6 months during 2 years. Each 6 months they will have a consultation by their physiologist with an echo or a CT-scan. At the same time, a 10ML blood sample will be taken to assess the circulating endothelial progenitor cells CD34+144+CD14- and CD34+VEGF-R2+CD14- blood level.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aortic aneurysm size >30mm and > 50mm

Exclusion criteria

• Infectious disease
• Inflammatory disease
• Liver insuffisency
• Cancer evolutive
• Pregnant women

Trial design

40 participants in 1 patient group

Aortic aneurysm

Description:

Patients with aortic aneurysm \>30mm and \< 50mm