Circulating Factors in Nephrotic Syndrome

Iain Bressendorff

Status: Not yet enrolling

Conditions: Minimal Change Disease; Membranous Nephropathy; Primary Focal Segmental Glomerulosclerosis; Nephrotic Syndrome

Treatments: Other: Observation

Study type: Observational

Funder types: Other

Identifiers

NCT06315504

Nephrotic Syndrome Cohort

Details and patient eligibility

About

A prospective observational study to investigate the treatment-associated changes of circulating factors associated with glomerular diseases among patients with de novo nephrotic syndrome admitted to hospital for a kidney biopsy.

Enrollment: 104 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Plasma albumin < 36 g/L
• Urine protein >3.5 g/day or urine protein/creatinine-ratio (UPCR) > 3.5 or urine albumin/creatinine-ratio (UACR) >2200 mg/g
• Planned kidney biopsy
• Able to give written informed consent

Exclusion criteria

• Kidney transplant recipient
• Previously undergone a kidney biopsy
• Unable to understand written information in Danish

Trial design

104 participants in 1 patient group

Patients with de novo nephrotic syndrome

Treatment:

Other: Observation