Circulating SIRT6 Expression, Effect on Aging Quality (Sirt6)

Civil Hospices of Lyon

Status: Completed

Conditions: Aging

Treatments: Biological: Blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT01567176

2011.674

Details and patient eligibility

About

This study follows the results of the COMPALICLAMP study (NCT00951392) where the investigators showed a differential expression of sirtuins protein isoforms, Sirt6, in muscle depending on the quality of aging. The investigators seek to confirm this difference in expression level of circulating leukocytes on a larger sample.

Enrollment: 60 patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Volunteers from the SUVIMAX 2 aging cohort
• Men and women
• Older than 60
• Subject with a global aging quality score of 1 or 3 in the SU.VI.MAX. 2 study
• Covered by Health Insurance System

Exclusion criteria

• Subject not in compliance with the recommendation of French National Law

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

Single Arm

Other group

Treatment:

Biological: Blood sample