Circulating Tumor Cells as a Biomarker for Preoperative Prognostic Staging in Patients With Esophageal Cancer

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Resectable Esophageal Cancer

Treatments: Procedure: esophagectomy

Study type: Observational

Funder types: Other

Identifiers

NCT01858805

CTC-EC

184

Details and patient eligibility

About

Despite the availability of several preoperative diagnostic techniques, accurate pretreatment staging of esophageal cancer (EC) remains challenging. Therefore, The investigators evaluated the prognostic significance of circulating tumor cells (CTCs) in patients with EC.

Enrollment: 123 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• > 18 years
• resectable esophageal cancer

Exclusion criteria

• < 18 years
• esophageal cancer with preoperative distant metastases

Trial design

123 participants in 1 patient group

detection of circulating tumors cells

Description:

This prospective, single-institution study conducted at the University Hospital Hamburg-Eppendorf (Hamburg, Germany) enrolled 123 patients with ECs that were initially considered resectable. Only patients with histologically proven EC were included. Peripheral blood samples for CTC analysis were collected immediately before surgery.

Treatment:

Procedure: esophagectomy