Circulating Tumor Cells (CTC) in Cancer

University Hospital Basel

Status: Enrolling

Conditions: Cancer

Treatments: Other: Blood samples; Other: Samples from tumor draining vessels

Study type: Observational

Funder types: Other

Identifiers

NCT04520672

2020-00014 me19Vetter;

Details and patient eligibility

About

This observational study with circulating tumor cells (CTC) count, isolation and analysis at several time points during disease progression is to investigate the role and biology of CTCs and clusters of CTCs in different cancer types. It also evaluates the role of CTCs as biomarkers, and aims at the identification of key signaling networks that are active in CTCs.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult cancer patients
• All patients with histology-based proved diagnosis of cancer, all stages and subtypes can be included. Precancerous lesions cannot be included.
• All patients with the diagnosis of a solid tumor including adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma, sarcoma
• Written pathology report must be available.
• Written informed consent.

Exclusion criteria

• No written informed consent.
• No proved diagnosis of malignancy by pathology report.
• Patients with the diagnosis of blood cancer