Citicoline, Creatine, and Omega-3 Effects in Middle Age Women

Deborah Yurgelun-Todd

Status: Completed

Conditions: Cognitive Benefits

Treatments: Drug: Citicoline, Omega-3 Fatty Acids and Creatine

Study type: Interventional

Funder types: Other

Identifiers

NCT01502813

IRB_48136

Details and patient eligibility

About

The purpose of this study is to determine the functional effects of a citicoline, creatine, and omega-3 fatty acids combination when administered for a duration of four weeks (28 days) to non-psychiatric adult female participants.

Full description

Standard clinical measures for mood and neuropsychological measures of attention, cognitive inhibition and memory will be applied before, during, and after a course of a daily supplementation of citicoline, creatine and omega-3 for 28 days to non-psychiatric adult female participants. We hypothesis that the combination of supplements will improve memory and attention in healthy adult women.

Enrollment: 40 patients

Sex: Female

Ages: 40 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female
• Age 40-60 years

Exclusion criteria

• Significant medical condition
• History of co-morbid psychiatric disorders
• Current Axis I or II diagnosis
• Past participation in a pharmacotherapeutic trial
• Head injury with LOC>5 minutes
• Use of psychotropic medication
• History of fish allergies
• Medical condition associated with clinically significant decreases in coagulability
• Use of anticoagulant medication

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Citicoline, Creatine, and Omega-3 Arm

Experimental group

Description:

Each participant will be given a supplement log at the end of visit 1. They will be asked to complete the log during the 28 days to indicate that the daily dose of supplements were taken according to instructions. The study coordinator will check the log on the second and third visits as well as count the remaining supplement pills. If participants do not comply with the daily supplement schedule, then the PI will determine if the participant should be withdrawn from the study.

Treatment:

Drug: Citicoline, Omega-3 Fatty Acids and Creatine