Citicoline in Youth Alcohol Use Disorder

Medical University of South Carolina (MUSC)

Status and phase: Enrolling; Phase 2

Conditions: Alcohol Use Disorder

Treatments: Drug: Citicoline (cytidine diphosphate-choline); Drug: Placebo oral capsule

Study type: Interventional

Funder types: Other

Identifiers

NCT05870111

Pro00128800

Details and patient eligibility

About

The goal of this study is to evaluate how citicoline, an over-the-counter supplement, versus a placebo pill (i.e., an inactive pill) affects the immune system, brain, and cognition in adolescents who may use alcohol.

Enrollment: 56 estimated patients

Sex: All

Ages: 16 to 22 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion:

Age 16 to 22.

Call study team for additional screening and information.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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56 participants in 2 patient groups, including a placebo group

Citicoline

Experimental group

Description:

2000mg/day citicoline for 4 weeks, administered orally

Treatment:

Drug: Citicoline (cytidine diphosphate-choline)

Placebo

Placebo Comparator group

Description:

placebo capsule daily for 4 weeks, matched in appearance to citicoline to preserve double-blind, administered orally

Treatment:

Drug: Placebo oral capsule