CLARITY Imaging Study

Imperial College London

Status: Unknown

Conditions: Glaucoma

Treatments: Other: sodium hyaluronate eyedrops

Study type: Interventional

Funder types: Other

Identifiers

NCT03758859

18SM4868

Details and patient eligibility

About

OCT image quality is necessary to provide accurate diagnostic information to ophthalmologists. The increasing resolution of imaging techniques will require ever more high standards of optical transmission through the cornea and tear film. Given that lubricant drops can improve optical transmission through the cornea, this study will attempt to quantify this. The primary objective is to assess the effect of cross-linked sodium hyaluronate on OCT image quality compared to the effect of blinking alone.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients subjectively deemed to have poor image quality by the photographer

Exclusion criteria

• Patients with a known adverse reaction to any of the constituents of the XLHA
• Patients wearing contact lenses
• Patients who have used eyedrops in the past 2 hours

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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80 participants in 1 patient group

sodium hyaluronate eye drops

Experimental group

Description:

the randomly allocated eye will receive sodium hyaluronate drops, followed by a repeat OCT scan; images are then evaluated for clarity by the masked assessor.

Treatment:

Other: sodium hyaluronate eyedrops