Classification and Longitudinal Follow-up of Common Melanocytic Nevi With in Vivo Reflectance Confocal Microscopy

Sheba Medical Center

Status: Unknown

Conditions: Common Melanocytic Nevi

Treatments: Device: RCM imaging

Study type: Observational

Funder types: Other

Identifiers

NCT01194947

SHEBA-10-8015-AS-CTIL

Details and patient eligibility

About

Our working hypothesis is that reflectance confocal microscopy (RCM) can identify distinct subsets of melanocytic nevi that retain their distinctive pattern over time.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients visiting the Sheba Medical Center pigmented lesion clinic for skin examination
• Patients having at least three banal-appearing nevi, one on the upper back, one on the lower back and one on the lower extremity (excluding foot), which are amenable for RCM examination.

Exclusion criteria

• Patients who are unwilling or medically unable to lie down for 30 minutes.
• Pregnant women

Trial design

90 participants in 1 patient group

Study participants

Description:

patients 18 or older presenting to the Sheba Medical Center pigmented lesion clinic for skin cancer surveillance. Patients routinely undergo total skin examination that includes clinical and dermoscopic evaluation of skin lesions. Patients also routinely undergo annual total body digital photography that allows identification of new or changing lesions.

Treatment:

Device: RCM imaging