Clinial Application of Park et al.(The Knee 27 (2020) 1577-1584)'s Study

Yonsei University Health System (YUHS)

Status: Withdrawn

Conditions: Knee Osteoarthritis

Treatments: Procedure: pulsed radiofrequency ablation to conventional points group; Procedure: pulsed radiofrequency ablation to modifined points group

Study type: Interventional

Funder types: Other

Identifiers

NCT05202847

3-2021-0432

Details and patient eligibility

About

The goal of this study was to perform pulsed radiofrequency ablation with a modified target suggested in the cadaver study by Park et al. (The Knee 27 (2020) 1577-1584) on knee osteoarthritis patients, and to evaluate the effect of reducing the frequency of intravascular injection and reducing pain.

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. chronic knee pain that does not respond to conservative treatment (physiotherapy, oral analgesic, steroid intra-articular injection, Hyruan injection) for more than 6 months
2. A score of 6 or higher (out of 10) on the target knee's numerical rating scale
3. Knee osteoarthritis 1-4 confirmed in knee X ray within 6 months of study enrollment

Exclusion criteria

1. Systemic inflammatory diseases such as rheumatic diseases
2. uncontrolled diabetes
3. malignant tumor
4. If the target knee has a previous surgical history (arthroscopy, arthroscopy, autologous or allograft osteochondral transplantation and autologous cartilage cell transplantation, osteotomy, arthritis surgery)
5. Patients with lidocaine and contrast agent allergy
6. history of nerve block in the target knee within 2 weeks
7. Body mass index over 40 kg/m2
8. bleeding disorder
9. Pregnant/lactating women
10. Inability to understand informed consent and respond to research questionnaires due to cognitive impairment
11. Unable to read consent form (e.g. illiterate, foreigner, etc.)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Quadruple Blind

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0 participants in 2 patient groups

pulsed radiofrequency ablation to modified points group

Experimental group

Description:

pulsed radiofrequency ablation aimed at the adjusted target point of Park et al. under C-arm guidance

Treatment:

Procedure: pulsed radiofrequency ablation to modifined points group

pulsed radiofrequency ablation to conventional points group

Active Comparator group

Description:

pulsed radiofrequency ablation aimed at conventional target point under C-arm guidance

Treatment:

Procedure: pulsed radiofrequency ablation to conventional points group