Clinic Study of 18F-Al-NOTA-MATBBN in Cancer Diagnostics

Wuxi No. 4 People's Hospital

Status and phase: Unknown; Early Phase 1

Conditions: Prostatic Neoplasms; Breast Neoplasms

Treatments: Device: PET/CT; Drug: 18F-Al-NOTA-MATBBN PET/CT

Study type: Interventional

Funder types: Other

Identifiers

NCT03094897

Wuxi4PH

Details and patient eligibility

About

The purpose of this study is to determine whether 18F-Al-NOTA-MATBBN is safety and effective for cancer diagnosis.

Full description

Observe radiation dose to healthy volunteers and patients; the correlation between integrin level and tumor/metastases uptake.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Volunteers or patients with age more than 18 yeas;
2. The patients have been diagnosed with cancer or suspected with cancer;
3. It must fulfill the ethical requirements and subjects have signed an informed consent.

Exclusion criteria

1. Pregnancy or nursing mothers;
2. Having drugs or alcohol dependence;
3. Hypersensitive to the active or inactive ingredients of the study drug;
4. Having attended other drug clinical trials within three months;
5. Cardiac functional insufficiency;
6. Hepatic and renal function insufficiency;
7. Hypertensive patients with serious complications;
8. Endangering the safety of life.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

18F-Al-NOTA-MATBBN PET/CT

Experimental group

Description:

Imaging with 18F-Al-NOTA-MATBBN PET/CT

Treatment:

Drug: 18F-Al-NOTA-MATBBN PET/CT

Device: PET/CT