Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defects in the Knee Joint With the Use of Autogenous Cartilage Graft With PRP GF (Platelet-rich Plasma With Growth Factors)

E

eMKa MED Medical Center

Status

Enrolling

Conditions

Knee Injuries
Cartilage Injury
Cartilage Damage

Treatments

Procedure: Arthroscopic reconstruction of the cartilage defects of the knee joint using the microfracture method
Procedure: Arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage transplant with PRP GF (platelet plasma with growth factor)

Study type

Interventional

Funder types

Other

Identifiers

NCT05328674
KB-563/2021

Details and patient eligibility

About

Clinical and comparative evaluation of the treatment results of arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage graft with PRP GF (platelet-rich plasma with growth factors)

Full description

The main goal of the research project is to evaluate the results of the treatment of arthroscopic reconstruction of cartilage defects in the knee joint with the use of an autogenous PRP GF cartilage graft. The specific objectives are: to compare the results of treatment of analogous areas of the cartilage defects of the knee joint obtained in the study groups using two methods: microfracture and autogenous PRP GF cartilage graft (Auto Cart-Arthrex method). The results on the operated limb will be compared in both groups both between the groups and with the results of clinical and biomechanical tests on non-operated limbs.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age 18-65 years;
  • Surgery for ACL damage to the knee joint;
  • Arthroscopic surgery;
  • No prior knee surgical interventions;
  • No additional pathologies in this anatomical area;
  • Informed consent of the patient to participate in the study.

Exclusion criteria

  • Age under 18 or over 65;
  • Previous surgical interventions in the examined anatomical area;
  • Additional pathologies in this area identified as part of preoperative diagnostics;
  • Damage to the second knee joint;
  • Failure to comply with the rigor of the same rehabilitation treatment protocol.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups

Microfracture method
Active Comparator group
Treatment:
Procedure: Arthroscopic reconstruction of the cartilage defects of the knee joint using the microfracture method
Method of autogenous PRP (Auto Cart-Arthrex) cartilage transplant
Experimental group
Treatment:
Procedure: Arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage transplant with PRP GF (platelet plasma with growth factor)

Trial contacts and locations

1

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Central trial contact

Maciej Kentel, MD PhD; Kacper Kentel, Master's degree

Data sourced from clinicaltrials.gov

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