Clinical And Cost- Effectiveness of Allium Sativum Oil (Garlic Oil ) Versus Mineral Trioxide Aggregate in Primary Molars Pulpotomy in Group of Egyptian Children : A Randomised Clinical Pilot Study.

Cairo University (CU)

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Carious Primary Molars

Treatments: Drug: Mineral Tri-Oxide Aggregate; Drug: Allium Sativum Oil

Study type: Interventional

Funder types: Other

Identifiers

NCT04903808

Lobnamagdy128

Details and patient eligibility

About

Allium Sativum oil is advocated to prove the capability of new natural products in replacing higher cost pharmacological materials, while achieving the same successful clinical and radiographic long-term results.

Full description

One of the most challenging subjects in paediatric dentistry is choosing the ideal pulp medication material that has the required properties such as preserving the vitality of the remaining intact pulp and stimulating its repair. This material should prevent pathological root resorption.Clinical and cost effectiveness trials from different countries are useful to determine which medicament should be advocated in which economic setting . Alternative pulpotomy materials clinically effective as MTA but with lower cost should be studied .

Enrollment: 26 estimated patients

Sex: All

Ages: 5 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Apparently healthy children aged from 5- 7 years.
• Children not having antibiotics in the past 14 days.
• Cooperative children.
• Children are having at least two carious asymptomatic second primary molars.

Exclusion criteria

• Uncooperative children.
• Immunocompromised children.
• Children with clinical or radiographic symptoms

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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26 participants in 2 patient groups

Allium sativum oil

Experimental group

Description:

The pulp stumps of the molars are dressed with a cotton pellet that is made damp with Allium Sativum oil for 1 min .

Treatment:

Drug: Allium Sativum Oil

Mineral Trioxide Aggregate

Active Comparator group

Description:

The material will be prepared according to the manufacturer's instructions , applied to the pulp chamber and a moistened cotton pellet was placed over the MTA paste to allow the material to set.

Treatment:

Drug: Mineral Tri-Oxide Aggregate