Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries (SDF and AgF)
Status
Begins enrollment this month
Conditions
Incipient Caries
Treatments
Other: Silver Fluoride with LED light
Other: Local brand Egyptian Silver Diamine Fluoride
Other: Local brand Egyptian Silver Diamine Fluoride with LED light
Other: International Sliver Diamine Fluoride with LED light
Other: International Sliver Diamine Fluoride
Other: Silver Fluoride
Details and patient eligibility
About
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light application on caries arrest of initial enamel pits and fissure caries for permanent teeth of young adults
Enrollment
366 estimated patients
Sex
All
Ages
18 to 25 years old
Volunteers
No Healthy Volunteers
Inclusion criteria
- high caries risk dental students
- Males or females
- Medically free
- Not taking medication
- At least had one active carious tooth
- Posterior permanent teeth
- ICDAS 2
Exclusion criteria
- non-Egyptian students
- Lack of compliance
- Allergic reaction to the materials used
- Pregnancy
- Dental students cannot give consent
- Teeth that will be extracted for orthodontic reasons
- Dental fluorosis
- Hypo calcified teeth
- Systemic diseases affecting teeth, such as amelogenesis imperfecta
- Severe periodontal affection
Trial design
Primary purpose
Prevention
Allocation
Randomized
Interventional model
Parallel Assignment
Masking
Single Blind
366 participants in 6 patient groups
Pits and fissures receive International Silver Diamine Fluoride for caries arrest
Active Comparator group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by International Silver Diamine Fluoride application for 60 seconds
Treatment:
Other: International Sliver Diamine Fluoride
Pits and fissures receive Local brand Egyptian Sliver Diamine Fluoride for caries arrest
Experimental group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by local brand Egyptian Silver Diamine Fluoride application for 60 seconds
Treatment:
Other: Local brand Egyptian Silver Diamine Fluoride
Pits and fissures receive Sliver Fluoride for caries arrest
Experimental group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Fluoride application for 60 seconds
Treatment:
Other: Silver Fluoride
Pits and fissures receive International Silver Diamine Fluoride with LED for caries arrest
Experimental group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Diamine Fluoride application for 10 seconds, followed by the application LED light for 20 seconds
Treatment:
Other: International Sliver Diamine Fluoride with LED light
Pits and fissures receive local brand Egyptian Silver Diamine Fluoride with LED for caries arrest
Experimental group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by local brand Egyptian Silver Diamine Fluoride application for 10 seconds, followed by LED light for 20 seconds
Treatment:
Other: Local brand Egyptian Silver Diamine Fluoride with LED light
Pits and fissures receive Sliver Fluoride with LED for caries arrest
Experimental group
Description:
Remineralization and prevention of incipient pits and fissure caries of permanent molars by Silver Fluoride application for 10 seconds, followed by application of LED light for 20 seconds
Treatment:
Other: Silver Fluoride with LED light
Trial contacts and locations
0
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Data sourced from clinicaltrials.gov
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