Clinical and Economical Assessment of an Intervention to Reduce Potentially Inappropriate Medication in Polymedicated Elderly Patients (REMEI)

Consorci Sanitari del Maresme

Status: Completed

Conditions: Polypharmacy; Elderly

Treatments: Procedure: Pharmacist Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT02275572

05/12

Details and patient eligibility

About

Objective: To evaluate the clinical and economic impact of the application of an algorithm to improve the adequacy and safety of pharmacotherapy in elderly polymedicated (receiving 8 or more medications), not institutionalized.

Design: randomized, open, multicenter and two branches of parallel intervention clinical trial.

Intervention Study: primary care pharmacist apply the GP-GP algorithm to each drug with the support of STOPP criteria, Beers and / or recommendations CatSalut. The pharmacist submit to doctor his findings and reach a consensus and decide which recommendations will be presented to patient. Control intervention: usual procedure.

Main outcome measures: a) Discontinued medications, changed or changing doses, b) GP consultations, hospital emergency department and hospital admissions for acute illness, c) pharmaceutical expenditure, d) restart medication e) complications underlying diseases. Follow-up control at 1 month (security) and at 3, 6 and 12 months.

Enrollment: 503 patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 70 years or more
• Currently receiving eight or more drugs, except ointments and administered via topical nonprescription
• Give their informed written consent to participate in the study.

Exclusion criteria

• Estimated life expectancy less than 6 months.
• Active cancer
• Participation in any other clinical trial or program for evaluation of medication in the elderly.
• Institutionalized in nursing homes.
• Surgical intervention scheduled for the next 6 months

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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503 participants in 2 patient groups

Pharmacist Intervention

Experimental group

Description:

Primary care pharmacist apply the GP-GP algorithm to each drug with the support of STOPP criteria, Beers and / or recommendations CatSalut. The pharmacist submit to doctor his findings and reach a consensus and decide which recommendations will be presented to patient.

Treatment:

Procedure: Pharmacist Intervention

Control

No Intervention group

Description:

Usual procedure.