Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

Yijing He

Status: Completed

Conditions: General Anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT02822417

2016 MZ/CSU/PS

Details and patient eligibility

About

To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

Full description

Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.

Enrollment: 1,453 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Aged more than 18 years;
2. General anesthesia for all patients;
3. Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery;
4. Patients were not delivered allogeneic blood in three months;
5. Having the ability to understand and sign the informed consent.

Exclusion criteria

1. Pregnant or lactating women;
2. Having an immune deficiency, as a patient with HIV infection;
3. Patients with infectious diseases, such as syphilis;
4. Patients delivered allogeneic blood in three months;
5. Researchers believe that may increasing the risk of subjects or interfering clinical trial;
6. Don't have the ability to understand or sign the informed consent.

Trial design

1,453 participants in 1 patient group

patients after general anesthesia

Description:

Laparoscopic surgery, orthopedics surgery or open surgery patients after general anesthesia