Clinical and Molecular Characteristics of Histiocytic Disorders

Mayo Clinic

Status: Enrolling

Conditions: Histiocytic Disorder

Treatments: Other: Non-Interventional Study

Study type: Observational

Funder types: Other

Identifiers

NCT06331377

17-004541 (Other Identifier)

NCI-2024-01765 (Registry Identifier)

Details and patient eligibility

About

This study is being done to collect medical and personal histories as well as a samples of blood, other body fluid and/or tumor/disease tissue for current and future research studies on histiocytic disorders.

Full description

PRIMARY OBJECTIVES:

I. Define molecular signature and genomic landscape of histiocytic disorders. II. Correlate genomic findings with transcriptional abnormalities. III. Identify promising prognostic alterations and potential therapeutic targets.

OUTLINE: This is an observational study.

Patients complete questionnaires and undergo blood and tissue sample collection. Patients' medical records are also reviewed.

Enrollment: 500 estimated patients

Sex: All

Ages: 1+ year old

Volunteers: No Healthy Volunteers

Inclusion criteria

• * All patients diagnosed with histiocytic disorders and age ≥1 year

Exclusion criteria

• * < 1 years age

Trial design

500 participants in 1 patient group

Observational

Description:

Patients complete questionnaires and undergo blood and tissue sample collection. Patients' medical records are also reviewed.

Treatment:

Other: Non-Interventional Study