Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin in the Preservation of Alveolar Ridge Following Atraumatic Tooth Extraction

Nahed Gamal Saleh Abdelaal

Status: Unknown

Conditions: Socket Preservation

Treatments: Procedure: Socket preservation with APRF; Procedure: natural healing

Study type: Interventional

Funder types: Other

Identifiers

NCT04197895

nana2019

Details and patient eligibility

About

compare the effect of application of A-PRF in socket preservation after atraumatic tooth extraction and natural healing regarding to bone remodeling . Null hypotheis, after atraumatic extraction, socket with advanced PRF has no difference with socket with blood clot in primary outcome

Enrollment: 36 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The inclusion criteria are as follow :

  • patients with an unremarkable medical history
  • subjects with at least one site bordered by minimum of one tooth.
  • Nonsmoker
  • Teeth with root fracture, teeth with failed endodontic therapy or advanced caries
  • Intact extraction socket with no dehiscence or fenestration.
  • The buccolingual thickness of the buccal plate of bone in surgical area is 1 mm or more

Exclusion criteria

• Patients with systemic diseases.
• Patients with presence or history of osteonecrosis of the jaws, with use of bisphosphonates, exposure to head and neck radiation, chemotherapy.
• patients with large distinct pre-apical pathology

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups

test group

Experimental group

Description:

Socket preservation with APRF

Treatment:

Procedure: Socket preservation with APRF

control group

Active Comparator group

Description:

natural healing

Treatment:

Procedure: natural healing