Clinical and Radiographic Evaluation of Nano Silver Fluoride Versus Calcium Hydroxide in Indirect Pulp Treatment (RCT)

Cairo University (CU)

Status: Completed

Conditions: Deep Caries

Treatments: Drug: Nano Silver Fluoride; Drug: Calcium hydroxide

Study type: Interventional

Funder types: Other

Identifiers

NCT04005872

Cairo U E

Details and patient eligibility

About

The management of deep carious lesions approaching a healthy pulp is considered a challenge to the dental practitioner. The conventional treatment of deep carious lesions requires the removal of all infected and affected dentin to avoid more cariogenic activity.

Full description

This study is designed to assess the clinical and radiographic effectivness of nano silver fluoride versus calcium hydroxide in an indirect pulp treatment of deep carious second primary molars. This clinical study is important because World Health Organization (WHO) has reported that school children experience to dental caries was 60-90% of worldwide (P. D. Garkoti et al., 2015).

This clinical trial has potential benefits to patients where indirect pulp treatment preserves pulp vitality by partial caries removal without exposing pulp. Several materials have been used for indirect pulp technique including calcium hydroxide (Metalita M et al., 2016).

Enrollment: 40 patients

Sex: All

Ages: 4 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients:

• Cooperative children.
• Both genders.
• In age range from 4 to 7 years.

Teeth:

• Vital second primary molars with deep caries limited to occlusal surface.
• No clinical signs or symptoms of irreversible pulpitis or pulp necrosis.
• No radiographic abnormalities
• Restorable teeth.

Exclusion criteria

• • Children with known history of allergy to any of the tested materials.

  • Children with systemic conditions.
  • Parents who refused to participate.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Nano Silver Fluoride

Experimental group

Description:

2 drops of nano silver fluoride (NSF) applied on the last soft carious layer using micro brush

Treatment:

Drug: Nano Silver Fluoride

Calcium Hydroxide

Active Comparator group

Description:

Calcium hydroxide placed on the last soft carious layer approaching the pulp

Treatment:

Drug: Calcium hydroxide