Clinical and Radiographic Evaluation of Natural Bovine Bone With Hyaluronic Acid on Osseointegration of Immediate Implant.

Suez Canal University

Status and phase: Completed; Phase 3; Phase 2

Conditions: Dental Implants

Treatments: Combination Product: immediate dental implant; Combination Product: immediate dental implant, natural bovine bone substitute material

Study type: Interventional

Funder types: Other

Identifiers

NCT07199725

544/2022

Details and patient eligibility

About

the goal of this study is to evaluate the effective of natural bovine bone with hyaluronic acid on osseointegration of immediate implants in single rooted badly decayed maxillary anterior teeth and premolars. the main question it aims to answer is does natural bovine with hyaluronic acid affects osseointegration of immediate implants.

the study compares immediate implants followed by grafting with natural bovine bone with hyaluronic acid to immediate implants without grafting.

Enrollment: 16 patients

Sex: All

Ages: 21 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• medically free patients, good oral hygiene, no periapical lesions around teeth to be extracted

Exclusion criteria

• patients with bone or soft tissue defects, poor oral hygiene, heavy smoking, bruxism, severe periodontal disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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16 participants in 2 patient groups

control group

Active Comparator group

Description:

control group: 8 immediate implants were inserted in 8 fresh extraction sockets without bone grafting.

Treatment:

Combination Product: immediate dental implant

study group

Active Comparator group

Description:

study group: 8 immediate implants were inserted in 8 fresh extraction sockets followed by grafting with natural bovine bone substitute material with hyaluronic acid

Treatment:

Combination Product: immediate dental implant, natural bovine bone substitute material