Clinical And Radiographic Evaluation Of Premixed Bio-ceramic MTA In Indirect Pulp Capping Of Young Permanent Molars

Cairo University (CU)

Status and phase: Not yet enrolling; Phase 3

Conditions: Indirect Pulp Capping

Treatments: Drug: Calcium hydroxide; Drug: Premixed Bio-ceramic MTA

Study type: Interventional

Funder types: Other

Identifiers

NCT05928858

14422022585603

Details and patient eligibility

About

The present study aims to evaluate the clinical and radiographic success of premixed bio-ceramic MTA versus calcium hydroxide in indirect pulp capping of young permanent molars.

Full description

Researchers are still in search of an ideal material for pulp capping, and they evaluated numerous dental materials. For many decades, calcium hydroxide has been the 'gold standard' material for maintaining pulp vitality. Both clinically and histologically, it has been found to produce satisfactory results in indirect and direct pulp capping because it can stimulate the formation of tertiary dentine by the pulp and it has antimicrobial properties.

Due to the drawbacks of calcium hydroxide, several materials have been developed, such as NeoPUTTY which is premixed bio-ceramic Mineral Trioxide Aggregate (MTA) that triggers hydroxyapatite. Its firm, non-tacky consistency, wash-out resistance, and bioactivity make it a pediatric dentists' preferred material for every pulp need. It also delivers ready-to-use material for immediate placement with zero waste, saving cost and chair time.

Enrollment: 40 estimated patients

Sex: All

Ages: 6 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who have young permanent molars with deep carious lesions.
• Restorable young permanent molars with no clinical symptoms of irreversible pulpitis.
• Permanent molars with no clinical or radiographic signs of pulp necrosis including swelling, fistula, pain on percussion,pathologic tooth mobility, thickening of the periodontal ligament space, radiolucency at the periapical area.

Exclusion criteria

• Medically compromised patients who have systemic disease.
• Uncooperative patients who refuse treatment
• Permanent molars that were previously restored
• Children whose parents or caregivers refuse to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Premixed Bio-ceramic MTA

Experimental group

Description:

Partial caries removal will be carried out then Premixed Bio-ceramic MTA will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration

Treatment:

Drug: Premixed Bio-ceramic MTA

Calcium hydroxide

Active Comparator group

Description:

Partial caries removal will be carried out then calcium hydroxide will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration

Treatment:

Drug: Calcium hydroxide