Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary Teeth (RCT)

Ain Shams University

Status: Completed

Conditions: Pulpitis - Irreversible

Treatments: Procedure: Pulpotomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04719247

PED19-3D

Details and patient eligibility

About

when caries reaches the pulp of the tooth, it has to be removed and replaced with a material. In this study im examining the clinical and radiographic signs and symptoms after using different natural materials in pulpotomized molars and compared to the formocresol.

Full description

Patients who have irreversible pulpitis and need pulpotomy will be selected randomly from the out patient clinic. they will be assigned randomly to different study and control groups. pulpotomy will be performed in the second primary molar and 1 of the five materials will be put in the pulp chamber (aloe vera, nigella sativa, thymus vulgaris, turmeric and formocresol). It will be covered with a restoration and a stainless steel crown. Patients follow up will be done after 1,3,6 and 12 months to assess clinical and radiographic signs and symptoms.

Enrollment: 90 patients

Sex: All

Ages: 4 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged from 4 to 7 years old
• Patients who are medically free
• Patients who have a restorable vital deep carious primary molar which is indicated for pulpotomy.
• No clinical signs or symptoms as pain on percussion, tooth mobility, presence of sinus or fistula, history of swelling.
• No radiographic signs of any periapical pathosis or signs of internal or external root resorption.

Exclusion criteria

• Patients who have any medical condition.
• Teeth that are badly broken down, that cannot be restored.
• Presence of uncontrolled bleeding.
• Clinical evidence of non-vitality such as presence of an abscess or a sinus or premature mobility.
• Radiographic evidence of bone resorption, internal or external root resorption and periapical or interradicular radiolucency.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 5 patient groups

Turmeric

Experimental group

Description:

Turmeric extract will be used as a dental pulp dressing material after pulpotomy and compared with Formocresol

Treatment:

Procedure: Pulpotomy

Thymus Vulgaris

Experimental group

Description:

Thymus Vulgaris extract will be used as a dental pulp dressing material after pulpotomy and compared with Formocresol

Treatment:

Procedure: Pulpotomy

Nigella Sativa

Experimental group

Description:

Nigella Sativa extract will be used as a dental pulp dressing material after pulpotomy and compared with Formocresol

Treatment:

Procedure: Pulpotomy

Aloe Vera

Experimental group

Description:

Aloe Vera extract will be used as a dental pulp dressing material after pulpotomy and compared with Formocresol

Treatment:

Procedure: Pulpotomy

Formocresol

Active Comparator group

Description:

Formocresol will be used as a dental pulp dressing material after pulpotomy to be compared with other materials.

Treatment:

Procedure: Pulpotomy