Clinical Aspect of Erosive Pustular Dermatosis of the Leg (Clin-EPDL)

CHU de Reims

Status: Completed

Conditions: Erosive Pustular Dermatosis of the Leg

Treatments: Other: Clinical examination

Study type: Observational

Funder types: Other

Identifiers

NCT03623191

2017Ao006

Details and patient eligibility

About

Erosive pustular dermatosis of the leg is a fairlyrecent clinical entity that was described the first time in 1987.

Diagnosis of erosive pustular dermatosis of the leg is made on clinical grounds. It presents as non-follicular pustules of variable size and numbers that rapidly give way to erosions and crusts on one or both legs, and which are found in particular on the anterior aspect of the middle third of the leg (. The lesions are of chronic progression, despite topical therapy. Erosive pustular dermatosis of the leg is seen in elderly patients, mainly female, and may be associated with chronic venous insufficiency or cutaneous atrophy. In the absence of specific criteria and because of the existence of misleading clinical forms, diagnosis is based upon exclusion.

Full description

The primary objective of this investigation was to describe the different clinical aspects of cases of Erosive pustular dermatosis of the leg.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• non-follicular pustules and multiple erosions on one or both legs showing no evidence of improvement after application of compression in the event of clinical signs of chronic venous insufficiency and showing no improvement following treatment with local and/or systemic antibacterial therapy, fungal samples from the pustules negative on direct examination, negative direct immunofluorescence results for biopsy samples (taken from around the lesion)

Exclusion criteria

• age < 18 years old

Trial design

45 participants in 1 patient group

Patients with erosive pustular dermatosis of the leg

Treatment:

Other: Clinical examination