Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling

Cairo University (CU)

Status and phase: Not yet enrolling; Phase 3; Phase 2

Conditions: Necrotic Pulp; Single Root Teeth

Treatments: Drug: MTA; Drug: resin sealer; Drug: bioceramic sealer

Study type: Interventional

Funder types: Other

Identifiers

NCT05419752

ENDO 23/5/2022

Details and patient eligibility

About

aim of the study will be conducted to compare the effect of MTA fill apex sealer and endo sequence bioceramic sealer in obturation on the intenisty of postoperative pain and the incidence of post operative swelling in patient with necrotic teeth .

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients requiring root canal treatment of single canal necrotic teeth.
• Patient from 18 to 60 years old
• Patients with Asymptomatic apical periodontitis.
• Teeth presenting with no clinical symptoms and with a periapical score from 2 to 4 according to Orstavik et al

Exclusion criteria

• Teeth with incompletely formed apex

  • Teeth requiring retreatment
  • Patients having complicating systemic disease such as diabetes, malignancy, pregnancy, central nervous system disorders, Cardiovascular system disorders, respiratory disorders, asthma patients, psychiatric disorders, immunocompromised patients
  • Patients taking anti-inflammatory or antibiotics
  • Patients giving history of analgesic or antibiotic intake 1 week before treatment
  • Patients below 18 years of age

• Patients above 65 years of age

  • Patients having history of peptic ulcer or gastrointestinal bleeding
  • Teeth affected with periodontal disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

endo sequence bioceramic sealer

Experimental group

Description:

obturation using Endo-sequence BC sealer

Treatment:

Drug: bioceramic sealer

MTA fill apex calcium silicate base sealer

Experimental group

Description:

obturation using calcium-silicates based MTA fill-apex sealer

Treatment:

Drug: MTA

AH plus resin sealer

Experimental group

Description:

obturation using AH Plus sealer

Treatment:

Drug: resin sealer