Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU (PR-Covid-19)

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Acute Respiratory Distress Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT04385004

7815 (Other Identifier)

Details and patient eligibility

About

Renal damage in patients hospitalized for ARDS in the ICU can also be related to multiple causes including, but not limited to, the consequences of hemodynamic fluctuations in these patients or the use of nephrotoxic drugs responsible for acute post-ischemic or toxic tubular necrosis. Frequently observed abnormalities of cioagumation may also have a potential impact on renal structures, particularly glomerular capillaries.

The researchers wish to characterize and phenotype the renal impairment of patients hospitalized in intensive care with tables of severe Covid19 infections in ARDS: clinical, biological and histological (by performing post-mortem biopsies).

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Enrollment: 320 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over 18 years of age
• Diagnosed Covid-19 by RT PCR
• Hospitalized in intensive care for management of complications related to Covid-19 from March 1, 2020 to April 20, 2020
• Patient not having expressed his or her opposition, after information, to the re-use of his or her data for the purposes of this research.

Exclusion criteria

• Subject who expressed opposition to participating in the study