Clinical Biological and Pharmacological Factors Influencing Stroke Outcome (biostroke)

University Hospital, Lille

Status: Completed

Conditions: Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT00763217

PHRC 2004/1901 (Other Identifier)

CP 05/15

Details and patient eligibility

About

In a previous suty, we have demonstrated that prior transient ischemic attack, treatment lipid-lowering drug or physical activity are associated to a better outcome of stroke. The aim of the study is to understand the mechanisms of this preventive neuroprotection by establishing link between biomarkers and preventive and neuroprotective measures.To answer to the question, we conduct a cohort study of stroke patients.

Full description

In the cohort, the severity of stroke (NIHSS) will be correlated with :

• clinical factors,
• pharmacological factors,
• biological factors (inflammatory markers, hemostasis...)

Enrollment: 550 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ischemic or hemorrhage stroke
• hemispheric stroke
• stroke dating from less 48h

Exclusion criteria

• non hemispheric stroke
• malformative intracranial hemorrhage
• traumatic intracranial hemorrhage
• subarachnoidal hemorrhage

Trial design

550 participants in 1 patient group

stroke patient cohort

Description:

Patients with an hemispheric ischemic or hemorrhage stroke hospitalized during the 48h following the beginning of stroke