Clinical Characteristics and Practice Patterns of Type 2 Diabetes Mellitus Patients Treated With OADs in Japan: Analysis of Medical and Health Care Database of the MDV

Boehringer Ingelheim

Status: Completed

Conditions: Diabetes Mellitus, Type 2

Treatments: Drug: oral antidiabetic drugs

Study type: Observational

Funder types: Industry

Identifiers

NCT03092752

1218.178

Details and patient eligibility

About

Appropriate use of oral antidiabetic drugs (OADs) including dose-reduction is important for patient's safety in T2DM patients with renal impairment (RI). However, there are insufficient data on dose adjustment in accordance with the prescription pattern and the risk of RI of OADs, in particular Dipeptidyl-peptidase-4 inhibitors, in clinical practice in Japan. Therefore, we will investigate OADs usage conditions and dose selection in T2DM patients with RI in clinical practice in Japan

Enrollment: 162,116 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with T2DM (ICD code: E11 or E14).
• Patients must have their first prescription (defined as index date*) for any study drugs between 01/01/2014 and 30/09/2016.
• Patients must have at least 6 months enrolment verified by the presence of any record except for the study drug prescriptions within the database (look back period) prior to the index date for each drug.

Exclusion criteria

• Patients who were under 40 years at the time of diagnosis of diabetes.
• Patients with record of type 1 diabetes mellitus.
• Patients who prescribed the study drugs during 6 month prior to index date for each drug.
• Patients whose mean visit interval are more than 92 days

Trial design

162,116 participants in 1 patient group

Patients with T2DM

Treatment:

Drug: oral antidiabetic drugs