Clinical Characteristics for the Critical Ill Patients With Klebsiella Pneumoniae Infection

Fujian Provincial Hospital

Status: Completed

Conditions: Drug Resistance

Study type: Observational

Funder types: Other

Identifiers

NCT04404582

K2019-06-031

Details and patient eligibility

About

The detection of Klebsiella pneumoniae virulence gene and antibiotics resistance gene takes a long time and high cost with equipment requirements. Distinguishing the Klebsiella pneumoniae by gene were late for clinical treatment. Therefore, the investigators aim to study the clinical characteristics of critically ill patients with Klebsiella pneumoniae infection which expressed different drug sensitivity test results.

Full description

Clinical data of adult patients in integrated ICUs of 6 hospitals of Fujian Province China from January 2015 to July 2019 were collected, who had been examined for sputum, urine, blood, pleural effusion, ascites, cerebrospinal fluid and wound secretions and other body fluid samples. And the results showed that Klebsiella pneumoniae was positive, including demographic data, underlying disease status, drug sensitivity test, infection-related indicators, life support, prognostic indicators.

Enrollment: 546 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult whose body fluid were sampled during ICU stay and Klebsiella pneumoniae was detected, followed by drug sensitivity test (including reporting the test results after the patient was transferred out of ICU or died).

Exclusion criteria

• Age were less than 18 years old;
• Patients stayed in ICU was less than 48 hours.

Trial design

546 participants in 1 patient group

Klebsiella pneumoniae

Description:

patients with Klebsiella pneumoniae infection had different results of the drug sensitivity test. we compared the prognosis of these patients.