Clinical Characteristics of Spinal Levobupivacaine: Hyperbaric Compared With Isobaric Solution

Mahidol University

Status: Completed

Conditions: Observation of Neuromuscular Block; Disease (or Disorder); Gynecological

Treatments: Drug: isobaric levobupivacaine; Drug: hyperbaric levobupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01349751

SiEC 197/2549

Details and patient eligibility

About

The authors would like to investigate the blocking characteristics, surgical quality and side effects of intrathecal levobupivacaine whether there are any differences between the hyperbaric and the isobaric formulation for gynaecologic surgeries which need higher block level than the urological surgeries.

Full description

The investigators study in the similar patients, give the same intervention except the baricity of levobupivacaine. The investigators record the level of sensory block and modified Bromage score for motor blockade.

Enrollment: 20 patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-III, aged 18-70 yr, scheduled for elective gynaecologic surgery, (total abdominal hysterectomy (TAH), TAH with uni-/bilateral salpingo-oophorectomy (SO), uni-/bilateral ovarian cystectomy, or myomectomy

Exclusion criteria

• contraindications for spinal block, body mass index (BMI) more than 35 kg/m2 and height less than 150 cm

Trial design

20 participants in 2 patient groups

isobaric levobupivacaine

Active Comparator group

Description:

spinal isobaric levobupivacaine

Treatment:

Drug: isobaric levobupivacaine

hyperbaric levobupivacaine

Active Comparator group

Description:

hyperbaric levobupivacaine

Treatment:

Drug: hyperbaric levobupivacaine