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Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually occurring at night or early morning. However, there are still some patients with only persistent clinical manifestations of chest tightness. Concerned about this group of patients, we presented a subgroup of bronchial asthma, namely, chest tightness variant asthma (CTVA). This asthma subgroup usually lacks asthma-specific clinical features such as wheezing, shortness of breath, wheezing, and therefore often misdiagnosed for a long time. In order to further understand the clinical characteristics, pathogenesis, and prognosis of patients with CTVA, we conducted a national multicenter observation study to further understand CTVA. Finally, we plan to clarify whether CTVA is a relatively independent asthma phenotype. Meanwhile, reducing misdiagnosis and perform an appropriate treatment of CTVA.
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all subjects agreed to participate, understand the project, observe the use of drugs, agree to follow-up, and signed informed consent;
the age of more than 14 and less 80 years old, gender and ethnicity are not limited;
the duration time was more than 6 months,and chest tightness was the only complaint, without breathing, short of breath, chronic cough;
no wheezing;
a diagnosis of asthma supported by one or more other characteristics:
bronchodilator and glucocorticoid treatment is effective;
exclude the following diseases by the corresponding doctors: coronary heart disease, myocarditis, heart failure, GERD, neuromuscular disease, and mental disease.
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Data sourced from clinicaltrials.gov
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