Clinical Comparative Trial of a Modified Polyurethane Dressing and Aquacel

Klinik Bogenhausen

Status: Completed

Conditions: Reepithelialization of Skin Graft Donor Sites

Treatments: Device: Aquacel® (ConvaTec, Skillman, NJ, USA), sodium carboxy-methylcellulose hydrocolloid polymer dressing; Device: modified polyurethane film dressing (OpSite, Smith&Nephew, London, UK)

Study type: Interventional

Funder types: Other

Identifiers

NCT01055925

MPV-AQUACEL

Details and patient eligibility

About

The almost single disadvantage of conventional polyurethane film dressings, an uncontrolled leakage, is probably as often described as its numerous advantages for split-thickness skin graft (STSG) donor sites. This shortcoming can be overcome by perforating the polyurethane dressing (MPD), which permits a controlled leakage into a secondary absorbent dressing. The study was conducted to compare the MPD-system and Aquacel® (ConvaTec), a hydrofiber wound dressing, which also seems to fulfill all criteria of an ideal donor site dressing.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• skin graft donor site anterolateral thigh
• men and women > 18 years

Exclusion criteria

• informed consent missing
• repeated skin graft take or prior injury at the observed site
• Subject unlikely to comply with protocol, e.g., uncooperative attitude, inability to return for follow-up visits, and unlikelihood of completing the study
• History of hypersensitivity to the investigational products

Trial design

0 participants in 2 patient groups

MPV

Active Comparator group

Treatment:

Device: modified polyurethane film dressing (OpSite, Smith&Nephew, London, UK)

Aquacel

Active Comparator group

Treatment:

Device: Aquacel® (ConvaTec, Skillman, NJ, USA), sodium carboxy-methylcellulose hydrocolloid polymer dressing