Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence

Utah System of Higher Education (USHE)

Status: Completed

Conditions: Anemia; Thrombocytopenia; Hypofibrinogenemia; Coagulopathy, Mild

Treatments: Behavioral: Clinical Decision Support

Study type: Interventional

Funder types: Other

Identifiers

NCT05634005

IRB_00156498

Details and patient eligibility

About

Determine whether clinical decision support (best practice advisory) improves provider adherence to transfusion guidelines for all four major blood components (red blood cells, plasma, platelets, and cryoprecipitate) using a randomized study design to reduce risk of bias. Alerts will be visible to the experimental ordering provider group, while they will not be visible to the control. Both groups still have access to information about best practices: local clinical transfusion guidelines are available and education on blood transfusion best practices will continue regardless of randomization assignment.

Enrollment: 1,543 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ordering providers that order at least one blood product in the electronic health record

Exclusion criteria

• Any individual without privileges to place an initial order for blood product(s)

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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1,543 participants in 2 patient groups

Ordering Providers Assigned to Visible Clinical Decision Support Alerts

Experimental group

Description:

Clinical decision support alert will fire and become visible to the ordering provider in the electronic health record if blood product(s) are ordered out of accordance with guidelines. Information about transfusion guidelines and best practices will be sent to providers prior to starting the study and will be available on an internal website.

Treatment:

Behavioral: Clinical Decision Support

Ordering Providers Assigned to No Visible Clinical Decision Support Alerts

No Intervention group

Description:

Clinical decision support alert will not be visible to the ordering provider in the electronic health record if blood product(s) are ordered out of accordance with guidelines. Information about transfusion guidelines and best practices will be sent to providers prior to starting the study and will be available on an internal website.