Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension (AI-HTN)

NeuroTherapia, Inc.

Status: Begins enrollment in 1 month

Conditions: Blood Pressure, High; Hypertension; Blood Pressure Control; Hypertension (HTN)

Treatments: Other: Standard medical treatment; Other: Clinical Decision Support Tool

Study type: Interventional

Funder types: Other

Identifiers

NCT07218198

V2.0 11Dec2025

Details and patient eligibility

About

The goal of this clinical trial is to study whether having a clinical decision support (CDS) tool available to clinician use will more effectively lower BP 4 weeks after an outpatient visit compared with usual care. The main objective is to assess the impact of the CDS tool, that is embedded with the electronic medical record (EMR), that is available during outpatient clinical encounters, on blood pressure (BP) changes among participants with uncontrolled hypertension.

Participants will:

Visit the clinic 4 weeks, after their initial clinician visit, for a BP check.

Enrollment: 168 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Men and women 18 years of age or older
2. Electronic Health Record (EHR) of hypertension AND prescribed at least one BP lowering medication
3. Office systolic BP of 130 mmHg or higher
4. Willing and able to comply with the study instructions AND attend a scheduled study visit

Exclusion criteria

1. Women who are pregnant, plan to become pregnant, or are breast-feeding
2. Know heart failure with reduced ejection fraction and a left ventricular ejection fraction of less than 40%
3. End-stage kidney disease currently undergoing renal replacement therapy, or an eGFR < 15ml/min/1.73m2
4. In the opinion of the investigator, any other condition that will preclude participation in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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168 participants in 2 patient groups

Standard of Care for Hypertension Management

Active Comparator group

Description:

Clinicians will use their own standard of care recommendations for combinations of medications.

Treatment:

Other: Standard medical treatment

Clinical Decision Support Tool

Experimental group

Description:

Clinical Decision Support Tool embedded into the Electronic Medical Record to help support clinicians to prescribe more effective combinations of medications

Treatment:

Other: Clinical Decision Support Tool