Clinical Deterioration in Cerebral Venous Thrombosis: A Predictive Study

Capital Medical University

Status: Completed

Conditions: Cerebral Venous Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT06266585

HX-B-2023090

Details and patient eligibility

About

The objective of this retrospective, prospective, multicenter cohort study is to determine the risk factors for deterioration of CVT patients after admission and establish a scoring model for risk stratification of patients. This study included two stages, the first stage was to enroll CVT patients from a single center from 2017 to 2022 for modeling, and the second stage was to enroll CVT patients from three centers in 2023 for external validation

Enrollment: 273 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age≥ 18 years old
• Patients were diagnosed with cerebral venous thrombosis (CVT) through imaging techniques such as Computed Tomography Venography (CTV), Magnetic Resonance Venography (MRV), or Digital Subtraction Angiography (DSA)
• The diagnostic algorithm for CVT conformed to the current guideline criteria

Exclusion criteria

• Patients who had performed endovascular treatment (EVT) or decompressive craniectomy (DC) before admission and those whose primary treatment was EVT or DC rather than conservative treatment after admission
• Patients with severe hepatic or renal insufficiency
• Patients with intracranial tumors
• Patients with other cerebrovascular diseases