Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology

Assiut University

Status: Active, not recruiting

Conditions: Acute Appendicitis

Treatments: Procedure: Appendectomy

Study type: Observational

Funder types: Other

Identifiers

NCT06834958

Clinical diagnosis of acute ap

Details and patient eligibility

About

The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis

Full description

2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects:

1. Inclusion criteria:

   patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal .

2. Exclusion criteria:

malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, ...): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed

Enrollment: 50 estimated patients

Sex: All

Ages: 14 to 60 days old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion

• Male or female patients é clinically diagnosed acute appendicitis with normal WBCS

Exclusion Criteria:

• complicated AA (perforation, peri appendicular abscess or suspicion of a tumor.

  2_inflammatory bowel diseases 3_inability to co-operate and give informed consent 4_diffuse peritonitis 5_Patients with serious comorbid conditions DM & renal insufficiency, serum creatinine > 150 μmol/l 6_Pregnant & lactating patient 7_Patients with advanced malignancies & pt on immunosuppressive drugs

Trial design

50 participants in 1 patient group

Patient included who have acute appendicitis clinically and normal WBCS count

Treatment:

Procedure: Appendectomy