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Clinical Echography in Emergency Prognostic Evaluation of Pulmonary Embolism: ECU -EP Study. (ECU-EP)

C

Centre Hospitalier Universitaire de Saint Etienne

Status

Withdrawn

Conditions

Embolism, Pulmonary

Treatments

Procedure: clinical echography (CE)

Study type

Observational

Funder types

Other

Identifiers

NCT03366519
1608163
2016-A01721-50 (Other Identifier)

Details and patient eligibility

About

Pulmonary Embolism (PE) is a frequent disease, the third cause of cardiovascular death after stroke and myocardial infarction. According to European guidelines of European Society of Cardiology (ESC) and of European Respiratory Society (ERS), the prognostic stratification of PE severity is mandatory as soon as PE is diagnosed. This stratification includes the hemodynamic status, and specific tools : the assessment of the sPESI score, and the evaluation of PE's impact on right ventricle (RV) : increased biomarkers (troponin, BNP) and right ventricle/left ventricle (RV/LV) ratio.

the RV/LV ration may be evaluated ideally by transthoracic echo (TTE), or by CT scan. Unfortunately, only 10% of patients with PE are evaluated with TTE by a cardiologist in the initial time of PE diagnosis. Hence, the CT scan is the most frequent way to assess RV/LV ratio. However, CT is not possible for all patients (patients with contra-indication) or may have difficulties to provide a clear assessment because of technical issues.

Then, there is a need for morphological evaluation of RV as soon as PE is diagnosed, in every clinical setting. The improvement in technologies allowed the development of clinical echography (CE) in emergency departments.

CE is already available, non-invasive, less expansive, and may be a good way to assess RV/LV ratio in patients with PE diagnosed in emergency departments.

The investigators propose a prospective, multicenter study to assess the sensitivity of CE in patients with PE, compared to CT scan to detect RV/LV ≥0.9.

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patients with pulmonary embolism confirmed
  • Simplified Pulmonary Embolism Severity Index (sPESI) ≥ 1

Exclusion criteria

  • Contra-indication to CT scanner
  • Patients with high-risk pulmonary embolism (shock, hypotension)
  • Simplified Pulmonary Embolism Severity Index (sPESI) =0

Trial design

0 participants in 1 patient group

patients with pulmonary embolism
Description:
patients with pulmonary embolism confirmed by tomography scan in emergency department
Treatment:
Procedure: clinical echography (CE)

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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