Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery

University of Oslo

Status and phase: Unknown; Phase 4

Conditions: Periodontitis; Dental Plaque; Periodontal Diseases

Treatments: Drug: Chlorhexidine 0.2%, Curasept; Drug: Chlorhexidine 0.2%, Corsodyl

Study type: Interventional

Funder types: Other

Identifiers

NCT04223076

2020/121314

Details and patient eligibility

About

Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions. Several 0.2% solutions are available on the market. This study aimed to compare effectiveness of two commercially available 0.2% chlorhexidine mouthwashes. Patients, that after initial periodontal therapy, had a need for two periodontal surgeries, will be invited to join. After one surgical session, the patient will receive one 0.2% chlorhexidine solution, and after the next surgical session the patient will receive the other 0.2% chlorhexidine solution. Plaque and gingivitis will be recorded, as well as side effects.

Enrollment: 31 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Periodontitis, stage III and IV

Exclusion criteria

Uncontrolled diabetes Systemic conditions associated with excessive bleeding Uncontrolled hypertension

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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31 participants in 2 patient groups

Chlorhexidine 0.2% mouthwash control

Experimental group

Description:

Chlorhexidine 0.2%, Corsodyl Intervention rinsing 60 sec twice daily

Treatment:

Drug: Chlorhexidine 0.2%, Corsodyl

Chlorhexidine 0.2% mouthwash with an Anti Discoloring System

Experimental group

Description:

Chlorhexidine 0.2%, Curasept Intervention rinsing 60 sec twice daily

Treatment:

Drug: Chlorhexidine 0.2%, Curasept