Clinical Effect of Phenytoin Mucoadhesive Paste on Wound Healing After Oral Biopsy

Shahid Beheshti University of Medical Sciences

Status and phase: Unknown; Phase 1

Conditions: Wound Healing; Pain

Treatments: Drug: Phenytoin paste; Drug: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01680042

Merck-023

Details and patient eligibility

About

several studies have investigated healing effect of phenytoin.In this study we investigate healing effect of phenytoin mucoadhesive paste comparing to the usual mucoadhesive paste after oral biopsy.

Enrollment: 40 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergone oral biopsy

Exclusion criteria

• systemic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

phenytoin paste

Active Comparator group

Description:

this group receives phenytoin paste after oral biopsy

Treatment:

Drug: Phenytoin paste

usual mucoadhesive paste

Placebo Comparator group

Description:

this group receives the usual mucoadhesive paste without phenytoin after oral biopsy

Treatment:

Drug: Placebo